And with a market cap of $2.5 billion, Kailera Therapeutics does not need to post significantly better efficacy results with its candidates than the likes of Eli Lilly and Novo Nordisk to be successful and see its share price soar
Key takeaways Mounjaro uses a dual-action mechanism on GIP and GLP-1 receptors, while Ozempic targets only GLP-1 receptors, leading to differences in effectiveness
Routine aspiration pulling back on the plunger to check for blood is generally considered unnecessary for subcutaneous injections in the shallow, low-vessel fat layer, and modern injection guidance for subcutaneous drugs such as insulin no longer recommends it
Discussion While the overall number of GLP-1 RA exposures increased during the study period, outcomes were largely benign, with the most common being no effect
Diabetes Care (2016) 39(11):202635
Forceful squirting sprays the liquid across the floor of the mouth, reducing the concentrated contact needed for optimal absorption
